Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 15/20 | 0.46 |
| ▸ | APOB | P04114 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038156 | 0.91 | MTTP (0.48) | MTTPAPOBKDM4ESMOGAA | |
| SCHEMBL7041617 | 0.90 | MTTP (0.52) | MTTPAPOBKDM4EGAAALDH1A1 | |
| SCHEMBL7114775 | 0.88 | MTTP (0.47) | MTTPAPOBKDM4EGAASMN1; SMN2 | |
| SCHEMBL7035887 | 0.86 | MTTP (0.46) | MTTPAPOBKDM4EGAAALDH1A1 | |
| SCHEMBL7046542 | 0.86 | MTTP (0.48) | MTTPAPOBKDM4E | |
| SCHEMBL7039772 | 0.85 | MTTP (0.53) | MTTPAPOBGAA | |
| SCHEMBL7041769 | 0.85 | MTTP (0.47) | MTTPAPOBKDM4EGAAALDH1A1 | |
| SCHEMBL7039275 | 0.85 | MTTP (0.46) | MTTPAPOBKDM4EGAAALDH1A1 | |
| SCHEMBL7046181 | 0.84 | MTTP (0.45) | MTTPAPOBKDM4ESMOGAA | |
| SCHEMBL7043296 | 0.84 | MTTP (0.57) | MTTPAPOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073836-A1 | Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073836-A1 | Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | MTTP, CETP, CES1 | MTTP 1/4885APOB 18/4885KDM4E 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.