Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | PAOX | Q6QHF9 | 8/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445713 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL12302053 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL24572062 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL16318219 | 1.00 | KDM4E (0.76) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13902111 | 0.98 | KDM4E (0.71) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL1687734 | 0.90 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL20434232 | 0.89 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL26279817 | 0.88 | KDM4E (0.59) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL14739904 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL1900654 | 0.87 | KDM4E (1.00) | KDM4EMAPK1HIF1AADRA1APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163194-B1 | SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-6441232-B1 | PREFERENTIAL FLUORINATION | F2 CHEMICALS LTD. (GB) | 2002-08-27 | — | — | US | disclosed |
| EP-1163194-A1 | SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS | F2 Chemicals Limited (GB) | 2001-12-19 | — | — | EP | disclosed |
| WO-2001053234-A1 | SELECTIVE NITROGEN FUNCTIONALISATION OF ORGANIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 2001-07-26 | — | — | WO | disclosed |