SCHEMBL7047202

SCHEMBL7047202

CC(O)C(C)N1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
FDPS P14324 2/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAOB P27338 2/20 0.32
CHRNB2 P17787 4/20 0.31
SLC6A2 P23975 4/20 0.31
CHRNB4 P30926 4/20 0.31
CHRNA3 P32297 4/20 0.31
CHRNA4 P43681 4/20 0.31
SLC6A3 Q01959 4/20 0.31
CHRNA1 P02708 3/20 0.31
CHRNG P07510 3/20 0.31
CHRNB1 P11230 3/20 0.31
CHRND Q07001 3/20 0.31
DPP7 Q9UHL4 1/20 0.30
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 2/20 0.30
CYP2D6 P10635 2/20 0.30
CYP2C9 P11712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15014381 1.00 SMN1; SMN2 (0.52) SMN1; SMN2FDPSMEN1KMT2AMAOB
SCHEMBL16687884 0.82 SMN1; SMN2 (0.43) SMN1; SMN2FDPSMAOBCHRNB2SLC6A2
SCHEMBL19286390 0.82 SMN1; SMN2 (0.43) SMN1; SMN2FDPSMAOBCHRNB2SLC6A2
SCHEMBL23483378 0.79 SMN1; SMN2 (0.42) SMN1; SMN2FDPSMAOBCYP1A2CYP3A4
SCHEMBL27504818 0.79 SMN1; SMN2 (0.44) SMN1; SMN2FDPSMEN1KMT2AMAOB
SCHEMBL28259536 0.79 SMN1; SMN2 (0.44) SMN1; SMN2FDPSMEN1KMT2AMAOB
SCHEMBL24233286 0.78 SMN1; SMN2 (0.40) SMN1; SMN2FDPSCYP1A2CYP3A4CYP2D6
SCHEMBL18704897 0.78 CHRNA7 (0.39) SMN1; SMN2CYP2D6KCNH2KDM4EALDH1A1
SCHEMBL2835413 0.78 SMN1; SMN2 (0.38) SMN1; SMN2FDPSMEN1KMT2AMAOB
SCHEMBL3554263 0.77 SMN1; SMN2 (0.36) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004564-B1 Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines BAYER AG (DE) 2003-04-16 EP disclosed
US-6268501-B1 CATALYTIC HYDROGENATION OF HYDROXYETHYL PYRIDINE, WHEREIN RUTHENIUM WHICH HAS BEEN TREATED BEFORE USE WITH REDUCING AGENT IS USED AS CATALYST TO FORM HYDROXYETHYL CYCLONEXANE THAT CONTAINS NITROGEN ATOM IN CYCLOHEXANE RING BAYER AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed
EP-1004564-A1 Process for the preparation of hydroxyethylcyclohexanes and hydroxyethylpiperidines Bayer Aktiengesellschaft (DE) 2000-05-31 EP disclosed