SCHEMBL7047337

SCHEMBL7047337

Cc1ccc(CN(O)Cc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.64
CNR2 P34972 5/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
TAS2R14 Q9NYV8 1/20 0.47
MCHR1 Q99705 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
CNR1 P21554 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPT P10636 1/20 0.45
AOC3 Q16853 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4967718 0.91 CYP2C19 (0.50) CYP2C19CNR2ALDH1A1TSHRTDP1
SCHEMBL10748300 0.89 CYP1A2 (0.53) CYP2C19CNR2ALDH1A1TSHRLMNA
Ethane SCHEMBL8336264 0.86 TSHR (0.56) CYP2C19CNR2ALDH1A1TSHRLMNA
SCHEMBL39645 0.86 CYP1A2 (0.55) CYP2C19CNR2ALDH1A1TSHRLMNA
Propane SCHEMBL9330390 0.84 TSHR (0.54) CYP2C19CNR2ALDH1A1TSHRLMNA
Ammonia Solution, Strong SCHEMBL28967895 0.84 CYP1A2 (0.53) CYP2C19CNR2ALDH1A1TSHRLMNA
Hydrochloric Acid SCHEMBL1876474 0.84 CYP1A2 (0.53) CYP2C19CNR2SMN1; SMN2ALDH1A1TSHR
SCHEMBL7048042 0.83 TP53 (0.61) CYP2C19CNR2ALDH1A1TSHRTAS2R14
SCHEMBL12763730 0.82 CYP2C19 (0.63) CYP2C19CNR2SMN1; SMN2ALDH1A1TSHR
SCHEMBL16710068 0.82 CYP2C19 (0.63) CYP2C19CNR2SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP claimed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP claimed
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP disclosed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US disclosed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP disclosed