SCHEMBL7047610

SCHEMBL7047610

CC1=CC2=C(C=CC=CC2c2cccc3ccccc23)C1[Si](C)(c1ccccc1)C1C(C)=CC2=C1C=CC=CC2c1cccc2ccccc12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053640 0.89 EGFR (0.30)
SCHEMBL7053085 0.89 SLC6A4 (0.33) SLC6A4
SCHEMBL7056338 0.89
SCHEMBL7054457 0.88 SLC6A4 (0.33) SLC6A4
SCHEMBL7056303 0.87
SCHEMBL7051336 0.86 SLC6A4 (0.32) SLC6A4
SCHEMBL7048711 0.86 SLC6A4 (0.32) SLC6A4
SCHEMBL7931206 0.81
SCHEMBL7052194 0.74
SCHEMBL7052083 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed