SCHEMBL7047666

SCHEMBL7047666

CC(=O)c1ccc(C)c(OC(=O)c2c3ccccc3nc3ccccc23)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
TP53 P04637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TSHR P16473 1/20 0.41
MAPT P10636 6/20 0.40
DHODH Q02127 1/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663373 0.88 PDE10A (0.49) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL8876118 0.86 PDE10A (0.44) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL38661829 0.82 MEN1 (0.49) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL1054774 0.82 MEN1 (0.49) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL6989336 0.79 KMT2A (0.42) PDE10AKMT2AMEN1TSHRMAPT
SCHEMBL7050086 0.79 MEN1 (0.44) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL8875098 0.78 TP53 (0.46) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL13632698 0.77 MEN1 (0.45) PDE10AKMT2AMEN1TP53HSD17B10
SCHEMBL38661527 0.77 MEN1 (0.51) PDE10AKMT2AMEN1HSD17B10TSHR
SCHEMBL7050675 0.77 KMT2A (0.58) PDE10AKMT2AMEN1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed