SCHEMBL7047841

SCHEMBL7047841

Cc1cc(F)ccc1OC(=O)c1c2ccccc2nc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
NPSR1 Q6W5P4 2/20 0.47
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 2/20 0.43
KDM4E B2RXH2 1/20 0.43
DHODH Q02127 3/20 0.43
PLA2G2A P14555 1/20 0.42
PKM P14618 1/20 0.42
PDE10A Q9Y233 1/20 0.41
PRNP P04156 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7046745 0.86 MAPT (0.49) MAPTNPSR1ALDH1A1POLBSMN1; SMN2
SCHEMBL8741600 0.82 DHODH (0.46) MAPTHTTDHODHPLA2G2A
Trifluoromethanesulfonic Acid SCHEMBL7047025 0.79 MAPT (0.42) MAPTNPSR1ALDH1A1POLBSMN1; SMN2
SCHEMBL8149932 0.78 GAA (0.47) MAPTNPSR1ALDH1A1POLBSMN1; SMN2
SCHEMBL7797045 0.77 MAPT (0.48) MAPTCYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL8875098 0.76 TP53 (0.46) MAPTNPSR1ALDH1A1POLBSMN1; SMN2
SCHEMBL7043070 0.76 MAPT (0.48) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL7050675 0.75 KMT2A (0.58) MAPTNPSR1CYP1A2CYP2C9ALDH1A1
SCHEMBL4421304 0.75 KMT2A (0.50) MAPTALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL1054774 0.75 MEN1 (0.49) MAPTNPSR1L3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed