Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.90 |
| ▸ | LCK | P06239 | 4/20 | 0.90 |
| ▸ | LYN | P07948 | 4/20 | 0.90 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.74 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.74 |
| ▸ | SRC | P12931 | 3/20 | 0.69 |
| ▸ | KDR | P35968 | 2/20 | 0.69 |
| ▸ | TEK | Q02763 | 1/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.65 |
| ▸ | PRKDC | P78527 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | TEC | P42680 | 4/20 | 0.63 |
| ▸ | BMX | P51813 | 4/20 | 0.63 |
| ▸ | ITK | Q08881 | 3/20 | 0.63 |
| ▸ | BLK | P51451 | 3/20 | 0.63 |
| ▸ | TXK | P42681 | 2/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586962 | 0.95 | BTK (1.00) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL6431516 | 0.95 | BTK (1.00) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL17713980 | 0.94 | BTK (0.98) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15915382 | 0.87 | BTK (0.84) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL2631407 | 0.87 | BTK (0.84) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL5801169 | 0.86 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL5803102 | 0.86 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22243281 | 0.86 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL22243244 | 0.86 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL29441896 | 0.86 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |