Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 6/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050588 | 0.92 | MAP2K1 (0.50) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7049500 | 0.91 | MAP2K1 (0.46) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4861013 | 0.91 | MAP2K1 (0.48) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4855339 | 0.88 | MAP2K1 (0.48) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL7047865 | 0.85 | MAP2K1 (0.44) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4860222 | 0.85 | MAP2K1 (0.47) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4862268 | 0.83 | MAP2K1 (0.53) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4862173 | 0.83 | MAP2K1 (0.50) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4861446 | 0.82 | MAP2K1 (0.59) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4863415 | 0.82 | MAP2K1 (0.49) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |