SCHEMBL70479

SCHEMBL70479

COC(=O)c1cn(-c2ccccc2)nc1C(=O)OC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.69
ALDH1A1 P00352 5/20 0.63
GAA P10253 2/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
MAPK1 P28482 3/20 0.62
KDM4E B2RXH2 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
TP53 P04637 1/20 0.62
ALOX15 P16050 1/20 0.62
HSD17B10 Q99714 1/20 0.62
KMT2A Q03164 4/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
MEN1 O00255 2/20 0.61
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
GLA P06280 1/20 0.51
NFKB1 P19838 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL716746 0.84 MAPT (0.69) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL25432048 0.83 MAPT (0.68) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL20023755 0.83 GAA (0.61) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL12264890 0.82 MAPT (1.00) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL12265096 0.81 MAPT (0.64) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL717852 0.81 MAPT (0.64) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL8408208 0.81 GAA (0.58) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL1639488 0.80 GAA (0.57) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL13606623 0.80 GAA (0.57) MAPTALDH1A1GAANPC1RAB9A
SCHEMBL14974267 0.80 KMT2A (0.62) MAPTALDH1A1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885ALDH1A1 1882/4885GAA 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.