Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461029 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6448635 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6454364 | 0.83 | MAPT (0.51) | TDP1RAB9AL3MBTL1PKMLMNA | |
| SCHEMBL6449943 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6448806 | 0.82 | MAPT (0.48) | SMN1; SMN2TDP1RAB9ALMNAKDM4E | |
| SCHEMBL6449741 | 0.80 | MAPT (0.46) | SMN1; SMN2TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6450451 | 0.78 | NPC1 (0.56) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6450244 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6452734 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1NPC1RAB9AALOX15 | |
| SCHEMBL6454586 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1NPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |