Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.73 |
| ▸ | TEK | Q02763 | 11/20 | 0.73 |
| ▸ | SRC | P12931 | 10/20 | 0.73 |
| ▸ | HCK | P08631 | 9/20 | 0.73 |
| ▸ | KDR | P35968 | 8/20 | 0.73 |
| ▸ | FLT3 | P36888 | 5/20 | 0.73 |
| ▸ | EGFR | P00533 | 3/20 | 0.73 |
| ▸ | FYN | P06241 | 2/20 | 0.73 |
| ▸ | LYN | P07948 | 2/20 | 0.73 |
| ▸ | CSK | P41240 | 2/20 | 0.73 |
| ▸ | BTK | Q06187 | 2/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.73 |
| ▸ | ABL1 | P00519 | 2/20 | 0.73 |
| ▸ | PLK4 | O00444 | 1/20 | 0.73 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.73 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.73 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.73 |
| ▸ | PAK4 | O96013 | 1/20 | 0.73 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048201 | 1.00 | LCK (0.73) | LCKTEKSRCHCKKDR | |
| SCHEMBL6459113 | 0.92 | LCK (0.83) | LCKTEKSRCHCKKDR | |
| SCHEMBL6459108 | 0.92 | LCK (0.83) | LCKTEKSRCHCKKDR | |
| SCHEMBL6459235 | 0.92 | LCK (0.83) | LCKTEKSRCHCKKDR | |
| SCHEMBL6459123 | 0.92 | LCK (0.83) | LCKTEKSRCHCKKDR | |
| SCHEMBL6459227 | 0.92 | LCK (0.83) | LCKTEKSRCHCKKDR | |
| Hydrochloric Acid SCHEMBL7850338 | 0.91 | LCK (0.82) | LCKTEKSRCHCKKDR | |
| Hydrochloric Acid SCHEMBL6466978 | 0.91 | LCK (0.82) | LCKTEKSRCHCKKDR | |
| Hydrochloric Acid SCHEMBL6465246 | 0.91 | LCK (0.82) | LCKTEKSRCHCKKDR | |
| Hydrochloric Acid SCHEMBL6466982 | 0.91 | LCK (0.82) | LCKTEKSRCHCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |