Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.52 |
| ▸ | SRC | P12931 | 16/20 | 0.52 |
| ▸ | TEK | Q02763 | 14/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.48 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430412 | 0.92 | SRC (0.58) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6430413 | 0.92 | SRC (0.58) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL7048602 | 0.91 | SRC (0.52) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL7147807 | 0.89 | LCK (0.50) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL5813018 | 0.83 | LCK (0.64) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL4854954 | 0.80 | SRC (0.76) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL4854947 | 0.80 | SRC (0.76) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6434974 | 0.80 | SRC (0.76) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL4824923 | 0.79 | LCK (0.80) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL4824918 | 0.79 | LCK (0.80) | LCKSRCTEKKDRLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |