Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861086 | 0.93 | MEN1 (0.67) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL7050185 | 0.92 | MEN1 (0.49) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4858671 | 0.90 | MEN1 (0.70) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4862713 | 0.86 | MAP2K1 (0.65) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL7050199 | 0.85 | MAP2K1 (0.53) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4863337 | 0.85 | MEN1 (0.70) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4856379 | 0.84 | MAP2K1 (0.66) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4860684 | 0.84 | MEN1 (0.55) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4857852 | 0.84 | MAP2K1 (0.66) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL4858660 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |