SCHEMBL7048873

CCCC(O)CONC(=O)c1cc(F)c(F)cc1Nc1ccc(I)cc1F.COCC(O)CONC(=O)c1cc(F)c(F)cc1Nc1ccc(I)cc1F.O=C(NOCC(O)C(F)(F)F)c1cc(F)c(F)cc1Nc1ccc(I)cc1F

nearest known ligand 0.50

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	MAP2K1	Q02750	20/20	0.50

▸	MAP2K2	P36507	4/20	0.50

▸	BRAF	P15056	1/20	0.50

▸	MAPK1	P28482	1/20	0.50

▸	MAP2K5	Q13163	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4856773	0.91	MAP2K1 (0.58)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4860304	0.90	MAP2K1 (0.59)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4863295	0.87	MAP2K1 (0.57)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL7052743	0.84	MAP2K1 (0.63)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4863426	0.84	MAP2K1 (0.61)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4862346	0.84	MAP2K1 (0.61)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4863876	0.84	MAP2K1 (0.55)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4851718	0.84	MEN1 (0.50)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4851594	0.83	MAP2K1 (0.62)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL4856973	0.83	MAP2K1 (0.48)	MAP2K1MAP2K2BRAFMAPK1MAP2K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1301472-A2	OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS	WARNER-LAMBERT COMPANY (US)	2003-04-16	—	—	EP	disclosed
WO-2002006213-A2	OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS	WARNER-LAMBERT COMPANY (US)	2002-01-24	—	—	WO	disclosed