Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082213 | 1.00 | NPC1 (0.43) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7082206 | 1.00 | NPC1 (0.43) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7049358 | 1.00 | NPC1 (0.43) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7081800 | 0.85 | NPC1 (0.47) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7042547 | 0.85 | NPC1 (0.47) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7081805 | 0.85 | NPC1 (0.47) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL7042549 | 0.85 | NPC1 (0.47) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR | |
| SCHEMBL312597 | 0.71 | CTDSP1 (0.51) | NPC1L3MBTL1ALDH1A1CYP2C19MAPT | |
| SCHEMBL312599 | 0.71 | CTDSP1 (0.51) | NPC1L3MBTL1ALDH1A1CYP2C19MAPT | |
| SCHEMBL28149239 | 0.71 | CYP2C19 (0.47) | NPC1L3MBTL1ALDH1A1CYP2C19EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109029-A1 | Process for the preparation of enantiomerically pure tertiary ss-hydroxycarboxylic acids or their esters | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2003-06-12 | — | — | US | claimed |
| EP-1298218-A1 | Process for the production of enantiomerically pure tertiary beta-hydroxy acids and esters | Consortium für elektrochemische Industrie GmbH (DE) | 2003-04-02 | — | — | EP | claimed |
| US-20030109029-A1 | Process for the preparation of enantiomerically pure tertiary ss-hydroxycarboxylic acids or their esters | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2003-06-12 | — | — | US | disclosed |