Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 10/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851717 | 0.88 | MAP2K1 (0.65) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4861933 | 0.87 | MAP2K1 (0.60) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL7052730 | 0.85 | MAP2K1 (0.50) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL7052710 | 0.82 | MAP2K1 (0.62) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4861781 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4856694 | 0.80 | MEN1 (0.54) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4863143 | 0.80 | MAP2K1 (0.59) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL4857449 | 0.80 | MAP2K1 (0.70) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4860913 | 0.79 | MAP2K1 (0.52) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 | |
| SCHEMBL7052179 | 0.79 | MAP2K1 (0.51) | MAP2K1MAP2K2RAF1PDGFRBCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | claimed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | claimed |