Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.78 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.66 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.65 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856753 | 0.97 | MAP2K1 (0.83) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4861033 | 0.93 | MAP2K1 (0.82) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL26892403 | 0.91 | MAP2K1 (0.70) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4856675 | 0.91 | MAP2K1 (0.94) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL7056183 | 0.90 | MEN1 (0.70) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL5390991 | 0.89 | MAP2K1 (0.69) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4858006 | 0.89 | PIM1 (0.71) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL7051631 | 0.88 | MAP2K1 (0.78) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL7052612 | 0.88 | MAP2K1 (0.69) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 | |
| SCHEMBL4861666 | 0.88 | MAP2K1 (1.00) | MAP2K1MAP2K2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |