Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 16/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054397 | 0.92 | MAP2K1 (0.48) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7053678 | 0.89 | MAP2K1 (0.46) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7053080 | 0.87 | MAP2K1 (0.56) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4853096 | 0.86 | MEN1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7050232 | 0.86 | MAP2K1 (0.53) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7048028 | 0.86 | MAP2K1 (0.52) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4853832 | 0.85 | MAP2K1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7049579 | 0.84 | MAP2K1 (0.51) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL7048826 | 0.84 | MAP2K1 (0.61) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL4861439 | 0.84 | MAP2K1 (0.71) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | claimed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | claimed |