Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.43 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CALCA | P06881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892181 | 0.95 | CALCRL (0.46) | CALCRLRAMP1CALCA | |
| SCHEMBL1197477 | 0.78 | CALCRL (0.37) | CALCRLRAMP1 | |
| SCHEMBL5567949 | 0.78 | CALCRL (0.37) | CALCRLRAMP1 | |
| SCHEMBL1197782 | 0.75 | CALCRL (0.38) | CALCRLRAMP1CALCA | |
| SCHEMBL1197802 | 0.73 | CALCRL (0.79) | CALCRLRAMP1CALCA | |
| SCHEMBL2766016 | 0.72 | CALCRL (0.74) | CALCRLRAMP1CALCA | |
| SCHEMBL2899062 | 0.72 | CALCRL (0.65) | CALCRLRAMP1CALCA | |
| SCHEMBL13929986 | 0.71 | CALCRL (0.56) | CALCRLRAMP1CALCA | |
| SCHEMBL2893791 | 0.71 | CALCRL (0.60) | CALCRL | |
| SCHEMBL2522624 | 0.70 | CALCRL (0.47) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092168-A1 | CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2004-10-28 | — | — | WO | disclosed |