SCHEMBL7051080

SCHEMBL7051080

Nc1nc(O)cc(S)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL5672040 0.89 NT5E (0.31)
SCHEMBL6898924 0.81
SCHEMBL95816 0.81
SCHEMBL9172126 0.78 NPC1 (0.37)
SCHEMBL29279639 0.78 NPC1 (0.37)
SCHEMBL29546940 0.78 NPC1 (0.37)
SCHEMBL10792756 0.75
SCHEMBL10707871 0.74
SCHEMBL18167353 0.74
SCHEMBL94169 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524214-B2 Polyal drug conjugates comprising variable rate-releasing linkers MERSANA THERAPEUTICS, INC. (US) 2013-09-03 US disclosed
US-8524214-B2 Polyal drug conjugates comprising variable rate-releasing linkers MERSANA THERAPEUTICS, INC. (US) 2013-09-03 US disclosed
WO-2010138719-A1 POLYAL DRUG CONJUGATES COMPRISING VARIABLE RATE-RELEASING LINKERS MERSANA THERAPEUTICS, INC. (US) 2010-12-02 WO disclosed
US-20100305149-A1 Polyal Drug Conjugates Comprising Variable Rate-Releasing Linkers MERSANA THERAPEUTICS, INC. (US) 2010-12-02 US disclosed
US-20100305149-A1 Polyal Drug Conjugates Comprising Variable Rate-Releasing Linkers MERSANA THERAPEUTICS, INC. (US) 2010-12-02 US disclosed
EP-1299397-A1 NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME LG Life Sciences Ltd. (KR) 2003-04-09 EP disclosed
EP-1077981-B1 NOVEL CEPHALOSPORIN COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME LG CHEMICAL LTD (KR) 2002-08-07 EP disclosed
WO-2002004464-A1 NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME LG LIFE SCIENCES LTD (KR) 2002-01-17 WO disclosed
CN-1300290-A Novel cephalosporin compounds, process for their preparation and antibacterial compositions containing them LG CHEMICAL LTD (KR) 2001-06-20 CN disclosed
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
EP-0530537-B1 Condensed pyrimidine derivatives, their production and use as antitumor agents TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-01-08 EP disclosed
US-5403843-A Pyrrolopyrimidinyalglutaminate derivatives and their use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-04-04 US disclosed
EP-0530537-A1 Condensed pyrimidine derivatives, their production and use as antitumor agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-10 EP disclosed
US-5089490-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4758556-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 US disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed