Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051310 | 1.00 | NPC1 (0.44) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL7052306 | 0.84 | MCL1 (0.51) | MAPTESR1ESR2KDM4EHSD17B10 | |
| SCHEMBL7051173 | 0.84 | ESR2 (0.46) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL7052303 | 0.84 | MCL1 (0.51) | MAPTESR1ESR2KDM4EHSD17B10 | |
| SCHEMBL7051172 | 0.84 | ESR2 (0.46) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL7052373 | 0.83 | ESR2 (0.45) | MAPTESR1ESR2KDM4EGAA | |
| SCHEMBL7048937 | 0.83 | ESR2 (0.45) | RAB9AMAPTESR1ESR2KDM4E | |
| SCHEMBL7052379 | 0.83 | ESR2 (0.45) | MAPTESR1ESR2KDM4EGAA | |
| SCHEMBL7048934 | 0.83 | ESR2 (0.45) | RAB9AMAPTESR1ESR2KDM4E | |
| SCHEMBL7052370 | 0.83 | ESR2 (0.45) | MAPTESR1ESR2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | disclosed |
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | disclosed |