Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862354 | 0.93 | MAP2K1 (0.47) | MAP2K2MAP2K1ABCB1KMT2AMEN1 | |
| SCHEMBL4853367 | 0.90 | MAP2K1 (0.52) | MAP2K2MAP2K1KMT2AMEN1TDP1 | |
| SCHEMBL4860576 | 0.88 | MEN1 (0.47) | MAP2K2MAP2K1ABCB1KMT2AMEN1 | |
| SCHEMBL4863043 | 0.86 | MAP2K1 (0.56) | MAP2K2MAP2K1MAPK1 | |
| SCHEMBL4861273 | 0.85 | MEN1 (0.49) | MAP2K2MAP2K1KMT2AMEN1TDP1 | |
| SCHEMBL7051395 | 0.85 | MAP2K1 (0.51) | MAP2K2MAP2K1MAPK1 | |
| SCHEMBL4862967 | 0.84 | MAP2K1 (0.47) | MAP2K2MAP2K1ABCB1KMT2AMAPK1 | |
| SCHEMBL4862073 | 0.84 | MEN1 (0.44) | MAP2K2MAP2K1ABCB1KMT2AMEN1 | |
| SCHEMBL4864335 | 0.83 | MAP2K1 (0.61) | MAP2K2MAP2K1ABCB1KMT2AMEN1 | |
| SCHEMBL4856739 | 0.83 | MAP2K1 (0.61) | MAP2K2MAP2K1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |