Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.56 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.53 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.52 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863494 | 0.90 | MAP2K1 (0.57) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL7050142 | 0.89 | MAP2K1 (0.59) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL4860276 | 0.89 | MAP2K1 (0.56) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL4859964 | 0.89 | MEN1 (0.52) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL4856644 | 0.87 | MAP2K1 (0.54) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL7051234 | 0.85 | MAP2K1 (0.54) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL4860487 | 0.85 | MAP2K1 (0.68) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL4857251 | 0.85 | MAP2K1 (0.74) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL7156640 | 0.83 | MAP2K1 (0.48) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL4856919 | 0.83 | MAP2K1 (0.72) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |