Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.34 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052709 | 0.93 | MAP2K1 (0.48) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4853613 | 0.93 | MEN1 (0.44) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL7047834 | 0.91 | MAP2K1 (0.43) | MAP2K1MAP2K2 | |
| SCHEMBL4863799 | 0.91 | MAP2K1 (0.53) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4860947 | 0.85 | MEN1 (0.49) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL4861906 | 0.84 | MAP2K1 (0.48) | MAP2K1MAP2K2MAP2K5 | |
| SCHEMBL4861179 | 0.84 | MAP2K1 (0.46) | MAP2K1MEN1KMT2ATDP1MAP2K2 | |
| SCHEMBL7054856 | 0.84 | MAP2K1 (0.51) | MAP2K1MAP2K2 | |
| SCHEMBL4860644 | 0.83 | MAP2K1 (0.59) | MAP2K1MAP2K2 | |
| SCHEMBL4858757 | 0.83 | MAP2K1 (0.56) | MAP2K1MEN1KMT2ATDP1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |