Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.53 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | SMC2 | O95347 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047897 | 0.92 | MAP2K1 (0.55) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL7052553 | 0.91 | MAP2K1 (0.57) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL7051408 | 0.91 | MAP2K1 (0.63) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL7047992 | 0.86 | MAP2K1 (0.47) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL4856547 | 0.86 | MAP2K1 (0.58) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL7055294 | 0.85 | MAP2K1 (0.53) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL4858796 | 0.85 | MAP2K1 (0.58) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL4859924 | 0.85 | MAP2K1 (0.58) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL4860732 | 0.85 | MAP2K1 (0.53) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB | |
| SCHEMBL4861076 | 0.83 | MAP2K1 (0.55) | MAP2K1MAP2K2CSNK2A2RAF1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |