Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466211 | 0.88 | MAPT (0.46) | ARMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6466727 | 0.83 | AR (0.60) | ARMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6466939 | 0.76 | AR (0.67) | ARMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6469593 | 0.75 | MAPT (0.43) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL6464447 | 0.73 | AR (0.53) | ARMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6466315 | 0.72 | AR (0.59) | ARMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL29071900 | 0.70 | AR (0.70) | ARMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2637904 | 0.68 | CNR1 (0.44) | MAPTMEN1POLBTHRBKMT2A | |
| SCHEMBL5730843 | 0.68 | GRIA2 (0.43) | ARKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL17503940 | 0.67 | NOTUM (0.71) | MAPTKDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |