Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.79 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.79 |
| ▸ | BRAF | P15056 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856556 | 0.97 | MAP2K1 (0.73) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4861551 | 0.91 | MAP2K1 (0.62) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4853558 | 0.89 | MAP2K1 (0.61) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4864335 | 0.89 | MAP2K1 (0.61) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL2721678 | 0.89 | MAP2K1 (1.00) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL29353563 | 0.89 | MAP2K1 (1.00) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4861250 | 0.88 | MAP2K1 (0.58) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4862385 | 0.86 | MAP2K1 (0.71) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL7051122 | 0.86 | MAP2K1 (0.59) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 | |
| SCHEMBL4863043 | 0.86 | MAP2K1 (0.56) | MAP2K1MAP2K2BRAFMAPK1MAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301472-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006213-A2 | OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |