Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501155 | 1.00 | TSHR (0.42) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL1126335 | 0.89 | — | — | |
| SCHEMBL18032583 | 0.81 | TSHR (0.44) | TSHRTHRBLMNAMEN1KMT2A | |
| SCHEMBL10727433 | 0.79 | TSHR (0.42) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL8624722 | 0.79 | TSHR (0.42) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL20658163 | 0.79 | TSHR (0.42) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL31161936 | 0.78 | TSHR (0.36) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL10731186 | 0.77 | — | — | |
| Phosphine SCHEMBL28963108 | 0.77 | TSHR (0.40) | TSHRTHRBLMNASMN1; SMN2HTT | |
| SCHEMBL16296172 | 0.77 | TSHR (0.40) | TSHRTHRBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |