Benzamide

Benzamide

SCHEMBL7052137

COCCONC(=O)c1cc(Br)c(F)c(F)c1Nc1ccc(I)cc1C.NC(=O)c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAP2K1 Q02750 18/20 0.52
MAP2K2 P36507 2/20 0.52
PIM1 P11309 1/20 0.47
CAMK2B Q13554 1/20 0.47
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4860685 0.92 MEN1 (0.60) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4851657 0.89 MEN1 (0.58) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4862790 0.85 MEN1 (0.55) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4854890 0.85 MAP2K1 (0.62) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL5396288 0.85 MEN1 (0.60) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4862493 0.84 MEN1 (0.58) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4854698 0.84 MAP2K1 (0.71) MAP2K1MAP2K2PIM1CAMK2BHDAC3
SCHEMBL5379856 0.83 MEN1 (0.58) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL4862032 0.83 MAP2K1 (0.62) MEN1KMT2ATDP1MAP2K1MAP2K2
SCHEMBL5384161 0.83 MEN1 (0.62) MEN1KMT2ATDP1MAP2K1MAP2K2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301472-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2003-04-16 EP claimed
WO-2002006213-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-24 WO claimed