Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812945 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| SCHEMBL4073010 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| SCHEMBL13799343 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| SCHEMBL4070956 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| SCHEMBL13799342 | 1.00 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| Hydrochloric Acid SCHEMBL7056385 | 0.99 | ADRB3 (0.43) | ADRB3ADRB1OPRK1KDM4E | |
| SCHEMBL7058117 | 0.94 | ADRB3 (0.44) | ADRB3ADRB1OPRK1 | |
| SCHEMBL7058116 | 0.94 | ADRB3 (0.44) | ADRB3ADRB1OPRK1 | |
| SCHEMBL7056462 | 0.90 | ADRB3 (0.44) | ADRB3ADRB1KDM4E | |
| SCHEMBL8076934 | 0.90 | ADRB3 (0.44) | ADRB3ADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940387-B1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0940387-A1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |