SCHEMBL7052425

SCHEMBL7052425

O=C(O)C=CC(=O)OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.39
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28165583 1.00 HCAR2 (0.39) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL7052421 0.92
SCHEMBL9063320 0.92
SCHEMBL9063314 0.92
SCHEMBL9245251 0.83 HCAR2 (0.48) HCAR2
SCHEMBL9245245 0.83 HCAR2 (0.48) HCAR2
SCHEMBL2954447 0.81
SCHEMBL2954451 0.81
SCHEMBL7539301 0.80 HCAR2 (0.48) HCAR2TSHR
SCHEMBL7539292 0.80 HCAR2 (0.48) HCAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
EP-1194479-A1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES Prometic Biosciences Inc. (CA) 2002-04-10 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
WO-2000077081-A1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES PROMETIC BIOSCIENCES INC. (CA) 2000-12-21 WO claimed
EP-2951220-A1 SALT-TOLERANT STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2015-12-09 EP disclosed
WO-2014121188-A1 SALT-TOLERANT STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2014-08-07 WO disclosed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed
EP-0219884-A2 Hard contact lens material Tomei Sangyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed