⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691332 | 0.67 | — | — | |
| SCHEMBL212558 | 0.62 | — | — | |
| SCHEMBL736129 | 0.62 | — | — | |
| SCHEMBL158403 | 0.62 | — | — | |
| Ethylene SCHEMBL28529003 | 0.62 | — | — | |
| SCHEMBL1019089 | 0.62 | — | — | |
| SCHEMBL8762693 | 0.61 | — | — | |
| SCHEMBL11412829 | 0.61 | — | — | |
| Bromide SCHEMBL6060838 | 0.61 | — | — | |
| SCHEMBL8762698 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946431-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | University of Pittsburgh - of the Commonwealth System of Higher Education (US) | 2022-02-09 | — | — | EP | claimed |
| CN-113811323-A | Modified hemoglobin molecules and uses thereof | 高等教育联邦系统-匹兹堡大学 | 2021-12-17 | — | — | CN | claimed |
| WO-2020206159-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-10-08 | — | — | WO | claimed |
| EP-0306943-B1 | Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity | NEORX CORP (US) | 1994-11-30 | — | — | EP | claimed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | claimed |
| US-4981979-A | IMMUNOLOGY | NEORX CORPORATION (US) | 1991-01-01 | — | — | US | claimed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | claimed |
| CN-110891611-B | Hydrogel crosslinked hyaluronic acid prodrug compositions and methods | 阿森迪斯制药公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230414770-A1 | HYDROGEL CROSS-LINKED HYALURONIC ACID PRODRUG COMPOSITIONS AND METHODS | ASCENDIS PHARMA A/S (DK) | 2023-12-28 | — | — | US | disclosed |
| US-11642415-B2 | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods | ASCENDIS PHARMA A/S (DK) | 2023-05-09 | — | — | US | disclosed |
| EP-3438118-B1 | PEPTIDE DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-20220185867-A1 | MODIFIED HEMOGLOBIN MOLECULES AND USES THEREOF | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-16 | — | — | US | disclosed |
| CN-108779146-B | Peptide derivatives and uses thereof | 东丽株式会社 | 2022-03-18 | — | — | CN | disclosed |
| EP-0329481-A2 | Anchimeric radiometal chelating compounds | NEORX CORPORATION (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0306943-A2 | Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity | NEORX CORPORATION (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4797491-A | SPACERS; BIOCHEMICAL | CETUS CORPORATION (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0284071-A2 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy | NEORX CORPORATION (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0240200-A2 | Cross-linking agents, their use and preparation | CETUS CORPORATION (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0188256-A2 | Metal radionuclide labeled proteins for diagnosis and therapy | NeoRx (US) | 1986-07-23 | — | — | EP | disclosed |
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |