Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7053894 | 0.99 | ADRB3 (0.48) | ADRB3ADRB1ROCK2ROCK1BCHE | |
| SCHEMBL8063492 | 0.89 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL7052755 | 0.89 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL7051979 | 0.88 | ADRB3 (0.47) | ADRB3ADRB1BCHE | |
| Hydrochloric Acid SCHEMBL7053949 | 0.87 | BCHE (0.46) | ADRB3ADRB1BCHE | |
| SCHEMBL7052359 | 0.86 | ADRB3 (0.47) | ADRB3ADRB1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL7057281 | 0.85 | ADRB3 (0.46) | ADRB3ADRB1BCHE | |
| Hydrochloric Acid SCHEMBL8071558 | 0.85 | ADRB3 (0.46) | ADRB3ADRB1BCHE | |
| SCHEMBL7056462 | 0.85 | ADRB3 (0.44) | ADRB3ADRB1 | |
| SCHEMBL8076934 | 0.85 | ADRB3 (0.44) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940387-B1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0940387-A1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |