Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431375 | 0.97 | GAA (0.62) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL11115045 | 0.87 | GAA (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL18603934 | 0.87 | POLB (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL9131619 | 0.87 | GAA (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL7807009 | 0.87 | GAA (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL30872202 | 0.87 | POLB (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL3384331 | 0.87 | GAA (0.53) | GAAPOLBTSHRMAP4K4AR | |
| SCHEMBL28625665 | 0.87 | AR (0.61) | GAAPOLBTSHRARSMN1; SMN2 | |
| SCHEMBL1162713 | 0.86 | GAA (0.72) | GAAPOLBTSHRARPDE4A | |
| SCHEMBL30441601 | 0.86 | GAA (0.72) | GAAPOLBTSHRARPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710387-A | Disulfonamide macrocyclic compound and synthesis method thereof | UNIV SOUTH CHINA NORMAL | 2015-06-17 | — | — | CN | claimed |
| JP-6279389-A | — | — | None | — | — | JP | disclosed |
| US-20170073460-A1 | POLYETHER KETONE COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-03-16 | — | — | US | disclosed |
| CN-104710387-A | Disulfonamide macrocyclic compound and synthesis method thereof | UNIV SOUTH CHINA NORMAL | 2015-06-17 | — | — | CN | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| JP-H06279389-A | AMIDINOPHENYL ETHER DERIVATIVE | TERUMO CORP | 1994-10-04 | — | — | JP | disclosed |
| US-5084085-A | Plant growth regulators | FMC CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |