Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.71 |
| ▸ | PTPRA | P18433 | 9/20 | 0.71 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054436 | 1.00 | PTPN1 (0.71) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6493779 | 0.96 | PTPN1 (0.76) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6493771 | 0.96 | PTPN1 (0.76) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6490951 | 0.88 | PTPN1 (0.74) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6500914 | 0.83 | PTPN1 (1.00) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6500915 | 0.83 | PTPN1 (1.00) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6503290 | 0.81 | PTPN1 (0.55) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6503288 | 0.81 | PTPN1 (0.55) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6502040 | 0.79 | PTPN1 (0.70) | PTPN1PTPRAPTPN2 | |
| SCHEMBL6496144 | 0.77 | PTPN1 (1.00) | PTPN1PTPRAPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020688-A1 | SELECTIVE PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-03-13 | — | — | WO | disclosed |