SCHEMBL7054501

SCHEMBL7054501

CN(C)C(=O)C[C@@H]1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C[C@H](CC(=O)N(C)C)N1C(=O)c1ncc(-c2cc[n+]([O-])cc2)cn1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.39
F2 P00734 3/20 0.38
PLAT P00750 1/20 0.35
KLKB1 P03952 1/20 0.35
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054505 1.00 F10 (0.39) F10F2PLATKLKB1PKM
SCHEMBL6735069 0.90 F10 (0.37) F10F2
SCHEMBL6734233 0.89 F10 (0.40) F10F2PLATKLKB1PKM
SCHEMBL6731787 0.89 F10 (0.38) F10F2
SCHEMBL6730493 0.87 F10 (0.53) F10F2
SCHEMBL6730490 0.87 F10 (0.53) F10F2
SCHEMBL6730335 0.83 F10 (0.41) F10F2
SCHEMBL6734093 0.80 F10 (0.49) F10F2
SCHEMBL6733976 0.79 F10 (0.45) F10F2PLATKLKB1
Hydrochloric Acid SCHEMBL6731175 0.78 F10 (0.44) F10F2PLATKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed