SCHEMBL7055347

SCHEMBL7055347

O=C(NOCCCO)c1cc(Cl)c(F)c(F)c1Nc1ccc(I)cc1F.O=C(NOCCO)c1cc(Cl)c(F)c(F)c1Nc1ccc(I)cc1F

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAP2K1 Q02750 20/20 0.75
MAP2K2 P36507 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4861756 0.98 MAP2K1 (0.76) MAP2K1MAP2K2
SCHEMBL4860863 0.96 MAP2K1 (0.76) MAP2K1MAP2K2
SCHEMBL4861807 0.89 MAP2K1 (0.81) MAP2K1MAP2K2
SCHEMBL4858823 0.89 MAP2K1 (0.64) MAP2K1MAP2K2
SCHEMBL4854971 0.89 MAP2K1 (0.62) MAP2K1MAP2K2
SCHEMBL7053952 0.88 MAP2K1 (0.62) MAP2K1MAP2K2
SCHEMBL7051381 0.87 MAP2K1 (0.96) MAP2K1MAP2K2
SCHEMBL4860571 0.87 MAP2K1 (0.65) MAP2K1MAP2K2
SCHEMBL4863091 0.87 MAP2K1 (0.80) MAP2K1MAP2K2
SCHEMBL4859788 0.86 MAP2K1 (0.67) MAP2K1MAP2K2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301472-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2003-04-16 EP disclosed
WO-2002006213-A2 OXYGENATED ESTERS OF 4-IODO PHENYLAMINO BENZHYDROXAMIC ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-24 WO disclosed