Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 3/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056347 | 0.82 | SMN1; SMN2 (0.42) | CYP1A1CYP1B1MAPTCYP19A1KDM4E | |
| SCHEMBL22571315 | 0.77 | CYP1A1 (0.46) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL7055971 | 0.75 | CYP1A1 (0.41) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL30701949 | 0.75 | CA9 (0.50) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL3674074 | 0.75 | CA9 (0.50) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL7056770 | 0.71 | CA1 (0.50) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL7051043 | 0.70 | CYP1A1 (0.43) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL8910062 | 0.68 | CYP1A1 (0.55) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL28322511 | 0.68 | CYP1A1 (0.44) | CYP1A1CYP1B1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL17041606 | 0.67 | AR (0.47) | MAPTPOLBKMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |