Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061550 | 0.92 | TSHR (0.32) | TSHRTHRBLMNA | |
| SCHEMBL9206028 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL95733 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL4395275 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL277225 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL7699808 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL107940 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL7697182 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL4399689 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB | |
| SCHEMBL4389498 | 0.76 | TSHR (0.61) | NAAAMEN1KMT2ATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994108-B1 | PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6197970-B1 | REACTING WITH SECONDARY OR TERTIARY AMINE; DEBLOCKING, DEPROTECTING | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0994108-A1 | PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |