Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527694 | 0.96 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10448434 | 0.93 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6568101 | 0.86 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7535904 | 0.84 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29177464 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL27646544 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL1069127 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL29096240 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL13266339 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL27626357 | 0.83 | TSHR (0.65) | TSHRNAAAHCAR2RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021466-B1 | POLYMERISATION PROCESSES AND PRODUCTS AND USES OF THE PRODUCTS | CIBA SPEC CHEM WATER TREAT LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6407161-B1 | Polymerization processes and products and uses of the products | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-18 | — | — | US | disclosed |