Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | DDT | P30046 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385597 | 1.00 | USP30 (0.45) | USP30MIFGPR6ACKR3RIPK2 | |
| SCHEMBL29384706 | 0.93 | USP30 (0.44) | USP30MIFGPR6GPR119 | |
| SCHEMBL70155 | 0.93 | USP30 (0.44) | USP30MIFGPR6GPR119 | |
| SCHEMBL83343 | 0.87 | MIF (0.38) | USP30MIFACKR3RIPK2DDT | |
| SCHEMBL29385002 | 0.81 | SCD (0.47) | USP30 | |
| SCHEMBL70138 | 0.81 | SCD (0.47) | USP30 | |
| SCHEMBL68333 | 0.80 | USP30 (0.49) | USP30GPR6GPR119NAMPT | |
| SCHEMBL29385527 | 0.80 | USP30 (0.49) | USP30GPR6GPR119NAMPT | |
| SCHEMBL70422 | 0.79 | USP30 (0.48) | USP30GPR6DGAT2 | |
| SCHEMBL70855 | 0.75 | SCD (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |