Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.65 |
| ▸ | PDE4A | P27815 | 9/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887989 | 1.00 | PDE4D (0.65) | PDE4DPDE4BPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL4018328 | 0.99 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2880752 | 0.90 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7163938 | 0.90 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7138827 | 0.85 | PDE4D (0.81) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7138822 | 0.85 | PDE4D (0.81) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7138819 | 0.85 | PDE4D (0.81) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5958819 | 0.85 | PDE4D (0.63) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2881689 | 0.84 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6693484 | 0.84 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098578-A2 | COMPOSITION COMPRISING A PDE4 INHIBITOR AND A TNF-ALFA ANTAGONIST SELECTED FROM INFLIXIMAB, ADALIMUMAB, CDP870 AND CDP517 | ALTANA PHARMA AG (DE) | 2004-11-18 | — | — | WO | disclosed |