Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803867 | 0.79 | MCHR1 (0.78) | MCHR1HTR2C | |
| SCHEMBL4201146 | 0.79 | MAPK1 (0.54) | — | |
| SCHEMBL4778597 | 0.78 | NPSR1 (0.37) | MCHR1ALDH1A1TP53 | |
| SCHEMBL6646105 | 0.77 | MCHR1 (0.52) | MCHR1ALDH1A1TP53HTR2C | |
| SCHEMBL7407460 | 0.77 | HTR1D (0.70) | MCHR1ALDH1A1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6648384 | 0.77 | HTT (0.48) | NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL4256379 | 0.77 | NPC1 (0.76) | NPC1ALDH1A1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6646036 | 0.76 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL6645493 | 0.76 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL4263220 | 0.76 | CHEK2 (0.54) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305304-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-07 | — | — | WO | disclosed |