Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017451 | 0.82 | KMT2A (0.47) | ESR1GLSACP3ALDH1A1MAPK1 | |
| SCHEMBL363983 | 0.81 | TSHR (0.48) | ESR1GLSNPC1ALDH1A1MAPK1 | |
| SCHEMBL7759607 | 0.80 | TSHR (0.36) | L3MBTL1NPC1ALDH1A1MAPK1NLRP3 | |
| SCHEMBL8833419 | 0.79 | ESR1 (0.46) | ESR1GLSACP3NPC1RAB9A | |
| SCHEMBL27911680 | 0.79 | ESR1 (0.44) | ESR1GLSACP3L3MBTL1ALDH1A1 | |
| SCHEMBL18300626 | 0.79 | ESR1 (0.44) | ESR1GLSACP3L3MBTL1ALDH1A1 | |
| SCHEMBL15669192 | 0.79 | MEN1 (0.47) | ALDH1A1 | |
| SCHEMBL7058954 | 0.79 | ESR1 (0.40) | ESR1ACP3L3MBTL1NPC1RAB9A | |
| SCHEMBL29101185 | 0.79 | ESR1 (0.40) | ESR1ACP3L3MBTL1NPC1RAB9A | |
| SCHEMBL14721160 | 0.78 | ESR1 (0.42) | ESR1GLSACP3L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006118-B1 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | DOW CORNING ASIA LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6175031-B1 | PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE | DOW CORNING ASIA, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-6111126-A | Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond | DOW CORNING ASIA, LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-1006118-A2 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | Dow Corning Asia, Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |