Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687446 | 1.00 | CYP2C19 (0.57) | CYP2C19HIF1ACYP1A2CYP2C9CHRM3 | |
| SCHEMBL295742 | 1.00 | CYP2C19 (0.57) | CYP2C19HIF1ACYP1A2CYP2C9CHRM3 | |
| SCHEMBL19130513 | 0.86 | CYP2C19 (0.46) | CYP2C19HIF1ACYP1A2CYP2C9CHRM3 | |
| SCHEMBL5898588 | 0.85 | MAPT (0.46) | CYP2C19HIF1ACYP1A2CYP2C9CHRM3 | |
| SCHEMBL2794969 | 0.83 | CYP2C19 (0.39) | CYP2C19HIF1ACYP1A2CYP2C9KIF11 | |
| SCHEMBL9393304 | 0.83 | CYP2C19 (0.52) | CYP2C19HIF1ACYP1A2CYP2C9LMNA | |
| SCHEMBL5929626 | 0.83 | CYP2C19 (0.39) | CYP2C19HIF1ACYP1A2CYP2C9KIF11 | |
| SCHEMBL4307361 | 0.83 | CYP2C19 (0.56) | CYP2C19HIF1ACYP1A2CYP2C9CHRM3 | |
| SCHEMBL5929544 | 0.81 | KCNA5 (0.46) | CYP2C19HIF1ACYP1A2CYP2C9LMNA | |
| SCHEMBL27989626 | 0.81 | KCNA5 (0.46) | CYP2C19HIF1ACYP1A2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941231-B1 | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI SPA (IT) | 2003-05-02 | — | — | EP | disclosed |
| US-6153758-A | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI S.P.A. (IT) | 2000-11-28 | — | — | US | disclosed |
| EP-0941231-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.p.A. (IT) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022484-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.P.A. (IT) | 1998-05-28 | — | — | WO | disclosed |