Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.56 |
| ▸ | WNT3A | P56704 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | PIR | O00625 | 1/20 | 0.44 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726294 | 0.95 | CTNNB1 (0.61) | CTNNB1WNT3AKDM4EPRKCIRAB9A | |
| SCHEMBL102518 | 0.88 | PRKCI (0.62) | CTNNB1WNT3AKDM4EPRKCIRAB9A | |
| SCHEMBL29793780 | 0.88 | PRKCI (0.62) | CTNNB1WNT3AKDM4EPRKCIRAB9A | |
| SCHEMBL24119388 | 0.85 | CTNNB1 (0.61) | CTNNB1WNT3AKDM4EPRKCIACHE | |
| SCHEMBL22025856 | 0.85 | CTNNB1 (0.61) | CTNNB1WNT3AKDM4EPRKCIACHE | |
| SCHEMBL20329998 | 0.85 | CTNNB1 (0.61) | CTNNB1WNT3AKDM4EPRKCIACHE | |
| SCHEMBL16742246 | 0.84 | PRKCI (0.61) | CTNNB1WNT3APRKCIACHERAB9A | |
| SCHEMBL875455 | 0.83 | CTNNB1 (0.67) | CTNNB1WNT3AKDM4EPRKCIACHE | |
| SCHEMBL31262479 | 0.83 | CTNNB1 (0.67) | CTNNB1WNT3AKDM4EPRKCIACHE | |
| SCHEMBL13596352 | 0.83 | KDM4E (0.77) | KDM4ERAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417197-A1 | FUNGICIDAL 1-BENZOXEPIN DERIVATIVES | Bayer CropScience S.A. (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014104-A1 | FUNGICIDAL 1-BENZOXEPIN DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2003-02-20 | — | — | WO | disclosed |
| US-5420273-A | Skin disorders and antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5300522-A | Treating inflammatory, allergic, rheumatic, immunological disorders | HOFFMANN-LA ROCHE INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5164387-A | Antitumor agents, skin disorders, antiinflammatory agents | HOFFMANN-LAROCHE INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5037825-A | Useful In The Treatment Of Neoplasms, Dermatoses And Aging Of The Skin | HOFFMANN-LA ROCHE INC. (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0350846-A2 | Condensed heterocyclic compounds and their use in therapy | F. HOFFMANN-LA ROCHE AG (CH) | 1990-01-17 | — | — | EP | disclosed |