SCHEMBL7057362

SCHEMBL7057362

C=CCN(CC=C)S(=O)(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.53
CNR1 P21554 1/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HTT P42858 3/20 0.50
TSHR P16473 1/20 0.50
MMP3 P08254 1/20 0.47
C5AR1 P21730 1/20 0.45
ESR1 P03372 1/20 0.44
PKM P14618 1/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.41
ALOX12 P18054 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258729 0.82 C5AR1 (0.64) CNR2CNR1MEN1KMT2AHTT
SCHEMBL24791584 0.79 MEN1 (0.53) CNR2CNR1MEN1KMT2AHTT
SCHEMBL9277957 0.79 ESR1 (0.62) CNR2CNR1MEN1KMT2AHTT
SCHEMBL6379113 0.79 CA12 (0.60) CNR2CNR1MEN1KMT2AHTT
SCHEMBL4262910 0.78 ESR1 (0.53) CNR2CNR1MEN1KMT2AHTT
SCHEMBL26483278 0.78 MEN1 (0.59) MEN1KMT2AHTTTSHRPKM
SCHEMBL24791591 0.77 MEN1 (0.51) CNR2CNR1MEN1KMT2AHTT
SCHEMBL24791564 0.77 SMN1; SMN2 (0.51) CNR2CNR1MEN1KMT2AHTT
SCHEMBL1464345 0.75 MEN1 (0.49) CNR2CNR1MEN1KMT2AHTT
SCHEMBL15898561 0.75 CNR2 (0.67) CNR2CNR1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499923-B1 Dental adhesive BAYER AG (DE) 1996-01-24 EP claimed
US-5354827-A (Meth)acrylic acid esters containign formamide groups, crosslinking agents, solvents and acid BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US claimed
EP-0499923-A1 Dental adhesive Heraeus Kulzer GmbH & Co.KG (DE) 1992-08-26 EP claimed
EP-0902066-B1 Curable coating compositions from oligomeric condensation products BAYER AG (DE) 2003-05-07 EP disclosed
US-6069227-A UNSATURATED POLYESTER HOMOPOLYMERS OF AN AROMATIC TRI- OR TETRA-CARBOXYLIC ACIDS AND DIHYDROXYALKYL (METH)ACRYLATES; MUCH IMPROVED ADHESION TO PLASTIC SURFACES, ESPECIALLY POLYCARBONATES; WEATHERPROOFING; OPTICS; MECHANICAL PROPERTIES BAYER A.G. (DE) 2000-05-30 US disclosed
EP-0794952-B1 POLYMERISABLE AROMATIC CARBOXYLIC ACID AND CARBOXYLIC ACID ANHYDRIDES WITH CYCLIC CARBONATE GROUPS AND COMPOSITIONS THAT CONTAIN THESE COMPOUNDS HERAEUS KULZER GMBH & CO KG (DE) 2000-02-23 EP disclosed
US-6001535-A PHOTOSENSITIVE RECORDING MEDIA; PRINTING PLATES AGFA GEVAERT AG (DE) 1999-12-14 US disclosed
WO-1999042078-A2 HARDENABLE DENTAL MATERIAL AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1999-08-26 WO disclosed
EP-0902066-A1 Curable coating compositions from oligomeric condensation products BAYER AG (DE) 1999-03-17 EP disclosed
US-5808104-A DENTAL FILLINGS WITH HIGH BONDING STRENGTH HERAEUS KULZER GMBH (DE) 1998-09-15 US disclosed
US-5763622-A DENTISTRY, LITHOGRAPHY; QUICK-CURING BAYER AG (DE) 1998-06-09 US disclosed
US-4744828-A CURABLE DENTAL FILLING BAYER AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
EP-0261520-A2 (Methyl)-acrylic-acid esters of siloxanes containing tricyclodecane groups BAYER AG (DE) 1988-03-30 EP disclosed
EP-0254185-A1 (Meth)acrylic acid derivatives of tricyclo[5.2.1.02.6]decanes containing urethane groups BAYER AG (DE) 1988-01-27 EP disclosed
US-4707504-A Porous fillers in polymerizable compositions BAYER AKTIENGESELLSCHAFT (DE) 1987-11-17 US disclosed
US-4665217-A DENTAL FILLERS AND COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1987-05-12 US disclosed
EP-0209700-A2 Tricyclodecane derivatives of methacrylic acid, and their use BAYER AG (DE) 1987-01-28 EP disclosed
EP-0206074-A2 Methacrylic-acid esters and their use BAYER AG (DE) 1986-12-30 EP disclosed
EP-0201778-A1 (Meth)-acrylic-acid esters and their use BAYER AG (DE) 1986-11-20 EP disclosed
EP-0201031-A2 (Meth)acrylic esters and their use BAYER AG (DE) 1986-11-12 EP disclosed