Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064516 | 0.92 | PRSS1 (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7059969 | 0.86 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6221817 | 0.83 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7064385 | 0.81 | F10 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7064510 | 0.78 | PRSS1 (0.50) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6224499 | 0.75 | F10 (0.60) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6224300 | 0.73 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6224834 | 0.73 | F10 (0.63) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6222788 | 0.73 | F10 (0.60) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6223414 | 0.72 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311476-A1 | AZA-AMINO ACID DERIVATIVES (FACTOR X A?-INHIBITORS 15) | MERCK PATENT GmbH (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016315-A1 | AZA-AMINO ACID DERIVATIVES (FACTOR XA-INHIBITORS 15) | MERCK PATENT GMBH (DE) | 2002-02-28 | — | — | WO | disclosed |