Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656763 | 1.00 | STS (0.50) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL8409267 | 0.94 | STS (0.51) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL12888961 | 0.92 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1236171 | 0.92 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1236173 | 0.92 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1659350 | 0.92 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1237598 | 0.86 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1237597 | 0.86 | STS (0.49) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL1657651 | 0.85 | KDM4E (0.52) | STSLMNAMAPTHSD17B1RECQL | |
| SCHEMBL8410997 | 0.84 | KDM4E (0.49) | STSLMNAMAPTHSD17B1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310509-A2 | Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use | Sri International (US) | 2003-05-14 | — | — | EP | disclosed |